CJC-1295 is a synthetic GHRH (growth hormone-releasing hormone) analog modeled on the body's native sermorelin. It comes in two forms — 'no DAC' (also called Modified GRF 1-29, ~30 min half-life) and 'with DAC' (Drug Affinity Complex, ~8-day half-life via albumin binding). Pairing CJC-1295 with Ipamorelin is one of the most-studied GH-release research stacks.
Researchers use CJC-1295 to study sleep depth, lean muscle accretion, and anti-aging markers. The no-DAC variant is preferred when matching natural pulsatile GH release; the DAC variant is favored when a steadier serum GH elevation is the research goal. Frequently paired with Sermorelin or Tesamorelin in comparative GHRH research.
GHRH (growth hormone releasing hormone) analog; stimulates pituitary GH release. DAC variant adds albumin binding for extended duration. Read our complete research hub for the full literature review, or jump to our best peptides for sleep article for comparator molecules.
Lumen Labs' CJC-1295 (no DAC) batch CJC-2604-A tested 99.0% purity by HPLC with mass-spec identity confirmation. For DAC variants, see our dosing guide — the protocols diverge significantly.
Every CJC-1295 listing on Peptide.best comes from a verified vendor that has passed our onboarding audit — GMP-licensed manufacturing facility, documented chain of custody, third-party Janoshik Analytical testing on every batch, and a published Certificate of Analysis. Lumen Labs (the seller on this listing) currently maintains a 4.9-star average across all their products. Compare the five live offers on the right side of this page — Peptide.best forces vendors to compete on price and purity for the same SKU, so you always see the best current deal at the top, with the COA-verified purity, shipping speed, and seller rating side-by-side. Looking for alternatives in the same sleep space? Ipamorelin and the other peptides listed under our Sleep category are the most commonly compared alternatives.
Ipamorelin · Sermorelin · Tesamorelin · MGF. See the peptide stacks page for full protocol writeups.
CJC-1295 has not been evaluated by the FDA for any indication. All statements on this page are based on published research and are not medical claims. Some products may be sold for research purposes only as marked. Consult a licensed healthcare provider before use. See our full disclaimer.
CJC-1295 has been the subject of growing peer-reviewed and preclinical research across the sleep domain. The current PubMed index returns several hundred citations spanning mechanism, dose-response, and adverse-event reporting.
Key references commonly cited in CJC-1295 research:
For a full reference list, see the Peptide.best Research Hub or the dedicated Sleep pillar article.
CJC-1295 no DAC: 100 mcg, 2–3x daily (pre-bed mandatory), 8–12 week cycle. With DAC: 1–2 mg per week. Both subcutaneous.
This product ships as lyophilized powder. Reconstitute with Bacteriostatic water (1mL) for stable refrigerated storage. Once reconstituted, use within 30 days; keep at 2–8°C.
For full protocols and stacking guidance, see our peptide dosing guides. Always start at the low end of the published range and titrate based on individual response. Half-life (~30 min (no DAC) or ~8 days (with DAC)) determines dosing frequency.
Transient flushing, head-rush, mild numbness/tingling, occasional injection-site redness. DAC variant has higher risk of fluid retention and persistent elevated IGF-1.
Do not use during pregnancy or lactation. Do not combine with other peptides without reviewing pharmacology. Consult a licensed healthcare provider before beginning any peptide research protocol. Discontinue immediately if any adverse reaction occurs and contact your provider.
Limited interaction data exists for most research peptides. Be especially cautious when combining with prescription medications affecting the same physiological pathway as CJC-1295 (sleep pathway).
Every batch of CJC-1295 sold on Peptide.best ships with a third-party Certificate of Analysis (COA) from Janoshik Analytical — the most-cited independent peptide testing lab in the research community.
For our overall testing process and chain-of-custody details, see Trust & Safety.
I've cycled CJC-1295 from a few vendors over the past year, and Lumen Labs's is the cleanest reconstitution I've seen — no haze, no precipitate, exact mass on the COA. Used it primarily for sleep work. Will reorder.
Started seeing measurable sleep improvement by week 3 of my protocol. Followed the standard dosing in the Peptide.best dosing guide. Cold-chain shipping arrived properly cooled. COA was emailed within 10 minutes of order confirmation.
Quality is excellent — COA matched the claim and the lyophilized cake was tight and dry. Only knock is I'd prefer a smaller vial — the reconstituted product has a 30-day fridge life and I don't always finish before that.
Did a side-by-side using independent third-party HPLC across three different vendors. Lumen Labs's came in highest on actual peptide content and lowest on residual solvent. Worth the modest premium.
A: CJC-1295 is sold on Peptide.best for research purposes where applicable. Legal status varies by jurisdiction. See our disclaimer for full details.
A: Timing depends on protocol, dose, and individual response. Most users report observable changes within 2–6 weeks of consistent dosing per the standard research protocols. See the Dosing & Protocol tab.
A: Yes — see commonly stacked peptides in the Overview tab, or browse our peptide stacks page for full protocol writeups.
A: Peptide.best aggregates verified vendors and forces them to compete in a single checkout. Vendors save on customer-acquisition cost; the savings pass to you. Every batch is still 3rd-party COA tested.
Lumen Labs is one of the six verified vendor partners on Peptide.best. They maintain a 4.9-star average rating across all products and submit every batch to third-party HPLC analysis before it ships.
All Lumen Labs products on Peptide.best ship from a GMP-licensed contract manufacturing facility and are tested by Janoshik Analytical. Cold-chain shipping is included on temperature-sensitive products.