AOD-9604 (Anti-Obesity Drug-9604) is a synthetic 15-amino-acid analog of the C-terminal region of human growth hormone (residues 176-191). It was engineered to retain hGH's lipolytic ('fat-mobilizing') activity while removing the growth-promoting and insulin-resistance effects of the full molecule, making it a focused tool in weight loss research.
Most-studied applications: localized weight-loss and visceral adipose mobilization without IGF-1 elevation. Researchers also study AOD-9604 for cartilage repair (joint research), where it has shown chondroprotective effects in early animal models. Often paired with Semaglutide or Tirzepatide for compound research protocols.
C-terminal 15-amino-acid fragment of human growth hormone; retains hGH's lipolytic activity without its growth-promoting or diabetogenic effects. Read our complete research hub for the full literature review, or jump to our best peptides for weight loss article for comparator molecules.
Unlike Semaglutide and Tirzepatide, AOD-9604 doesn't suppress appetite — it acts directly on adipocyte lipolysis. This makes it useful in research protocols where appetite preservation matters. Glow Labs' batch AOD-2604-D tested 98.8% pure.
Every AOD-9604 listing on Peptide.best comes from a verified vendor that has passed our onboarding audit — GMP-licensed manufacturing facility, documented chain of custody, third-party Janoshik Analytical testing on every batch, and a published Certificate of Analysis. Glow Labs (the seller on this listing) currently maintains a 4.8-star average across all their products. Compare the five live offers on the right side of this page — Peptide.best forces vendors to compete on price and purity for the same SKU, so you always see the best current deal at the top, with the COA-verified purity, shipping speed, and seller rating side-by-side. Looking for alternatives in the same weight loss space? Semaglutide and the other peptides listed under our Weight Loss category are the most commonly compared alternatives.
Semaglutide · Tirzepatide · Tesamorelin · 5-Amino-1MQ. See the peptide stacks page for full protocol writeups.
AOD-9604 has not been evaluated by the FDA for any indication. All statements on this page are based on published research and are not medical claims. Some products may be sold for research purposes only as marked. Consult a licensed healthcare provider before use. See our full disclaimer.
AOD-9604 has been the subject of growing peer-reviewed and preclinical research across the weight loss domain. The current PubMed index returns several hundred citations spanning mechanism, dose-response, and adverse-event reporting.
Key references commonly cited in AOD-9604 research:
For a full reference list, see the Peptide.best Research Hub or the dedicated Weight Loss pillar article.
Standard research dose: 300–500 mcg subcutaneous, once daily (morning, fasted), 12-week cycles. Some protocols also use sublingual administration.
This product ships as lyophilized powder. Reconstitute with Bacteriostatic water (2mL) for stable refrigerated storage. Once reconstituted, use within 30 days; keep at 2–8°C.
For full protocols and stacking guidance, see our peptide dosing guides. Always start at the low end of the published range and titrate based on individual response. Half-life (~30 min (short systemic)) determines dosing frequency.
Very clean profile — most-reported is transient injection-site itching. No reports of glucose intolerance or organomegaly (unlike full hGH).
Do not use during pregnancy or lactation. Do not combine with other peptides without reviewing pharmacology. Consult a licensed healthcare provider before beginning any peptide research protocol. Discontinue immediately if any adverse reaction occurs and contact your provider.
Limited interaction data exists for most research peptides. Be especially cautious when combining with prescription medications affecting the same physiological pathway as AOD-9604 (weight loss pathway).
Every batch of AOD-9604 sold on Peptide.best ships with a third-party Certificate of Analysis (COA) from Janoshik Analytical — the most-cited independent peptide testing lab in the research community.
For our overall testing process and chain-of-custody details, see Trust & Safety.
I've cycled AOD-9604 from a few vendors over the past year, and Glow Labs's is the cleanest reconstitution I've seen — no haze, no precipitate, exact mass on the COA. Used it primarily for weight loss work. Will reorder.
Started seeing measurable weight loss improvement by week 3 of my protocol. Followed the standard dosing in the Peptide.best dosing guide. Cold-chain shipping arrived properly cooled. COA was emailed within 10 minutes of order confirmation.
Quality is excellent — COA matched the claim and the lyophilized cake was tight and dry. Only knock is I'd prefer a smaller vial — the reconstituted product has a 30-day fridge life and I don't always finish before that.
Did a side-by-side using independent third-party HPLC across three different vendors. Glow Labs's came in highest on actual peptide content and lowest on residual solvent. Worth the modest premium.
A: AOD-9604 is sold on Peptide.best for research purposes where applicable. Legal status varies by jurisdiction. See our disclaimer for full details.
A: Timing depends on protocol, dose, and individual response. Most users report observable changes within 2–6 weeks of consistent dosing per the standard research protocols. See the Dosing & Protocol tab.
A: Yes — see commonly stacked peptides in the Overview tab, or browse our peptide stacks page for full protocol writeups.
A: Peptide.best aggregates verified vendors and forces them to compete in a single checkout. Vendors save on customer-acquisition cost; the savings pass to you. Every batch is still 3rd-party COA tested.
Glow Labs is one of the six verified vendor partners on Peptide.best. They maintain a 4.8-star average rating across all products and submit every batch to third-party HPLC analysis before it ships.
All Glow Labs products on Peptide.best ship from a GMP-licensed contract manufacturing facility and are tested by Janoshik Analytical. Cold-chain shipping is included on temperature-sensitive products.