5-Amino-1MQ 150mg (capsules) or 50mg powder · 5-Amino-1-Methylquinolinium (NNMT Inhibitor) · 99.0% Purity

What is 5-Amino-1MQ?

5-Amino-1MQ (5-Amino-1-Methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) — an enzyme whose activity rises with age and obesity, depleting both NAD+ precursors and methyl donors (SAM). Inhibiting NNMT preserves cellular NAD+ and methylation capacity, the dual basis for its anti-aging and weight loss research applications.

What is 5-Amino-1MQ used for?

Most-studied applications: adipocyte-targeted weight-loss (NNMT is highly expressed in white adipose tissue), muscle satellite cell function in aged subjects, and as a partner to direct NAD+ supplementation. Often stacked with NAD+ and MOTS-c for compound metabolic research, or paired with Semaglutide and Tirzepatide for compound fat-loss protocols.

How does it work?

Small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT); preserves cellular NAD+ pool and SAM availability; promotes adipocyte lipolysis and muscle satellite-cell function. Read our complete research hub for the full literature review, or jump to our best peptides for weight loss article for comparator molecules.

Why this listing?

Although technically a small molecule rather than a peptide, 5-Amino-1MQ has become a staple of the peptide-research community due to its mechanistic complementarity with NAD-axis peptides. Aeon Labs' batch 5AM-2604-E tested 99.0% pure by HPLC.

How Peptide.best sources and verifies 5-Amino-1MQ

Every 5-Amino-1MQ listing on Peptide.best comes from a verified vendor that has passed our onboarding audit — GMP-licensed manufacturing facility, documented chain of custody, third-party Janoshik Analytical testing on every batch, and a published Certificate of Analysis. Aeon Labs (the seller on this listing) currently maintains a 4.9-star average across all their products. Compare the five live offers on the right side of this page — Peptide.best forces vendors to compete on price and purity for the same SKU, so you always see the best current deal at the top, with the COA-verified purity, shipping speed, and seller rating side-by-side. Looking for alternatives in the same weight loss space? NAD+ and the other peptides listed under our Weight Loss category are the most commonly compared alternatives.

Commonly stacked with

NAD+ · MOTS-c · Epitalon · Semaglutide. See the peptide stacks page for full protocol writeups.

Compliance notice

5-Amino-1MQ has not been evaluated by the FDA for any indication. All statements on this page are based on published research and are not medical claims. Some products may be sold for research purposes only as marked. Consult a licensed healthcare provider before use. See our full disclaimer.

Research literature

5-Amino-1MQ has been the subject of growing peer-reviewed and preclinical research across the weight loss domain. The current PubMed index returns several hundred citations spanning mechanism, dose-response, and adverse-event reporting.

Key references commonly cited in 5-Amino-1MQ research:

• Mechanism papers covering small-molecule inhibitor of nicotinamide n-methyltransferase (nnmt); preserves cellular nad+ pool and sam availability; promotes adipocyte lipolysis and muscle satellite-cell function.
• Dose-response work in rodent models (most studied species)
• Comparator-molecule trials vs. NAD+ and other peptides in the same class
• Safety / pharmacovigilance datasets where available

For a full reference list, see the Peptide.best Research Hub or the dedicated Weight Loss pillar article.

Standard research dosing

Standard oral protocol: 150 mg, 1–2x daily, in 8–12 week cycles. Subcutaneous research protocols also documented (lower doses).

Reconstitution

This product ships as oral capsule (most common) or lyophilized powder. Reconstitute with N/A (oral) for stable refrigerated storage. Once reconstituted, use within 30 days; keep at 2–8°C.

Protocol notes

For full protocols and stacking guidance, see our peptide dosing guides. Always start at the low end of the published range and titrate based on individual response. Half-life (~6-8 hours) determines dosing frequency.

Reported side effects

Generally well-tolerated — occasional mild GI upset, transient warmth/flushing. Long-term human safety data is limited.

Contraindications

Do not use during pregnancy or lactation. Do not combine with other peptides without reviewing pharmacology. Consult a licensed healthcare provider before beginning any peptide research protocol. Discontinue immediately if any adverse reaction occurs and contact your provider.

Drug interactions

Limited interaction data exists for most research peptides. Be especially cautious when combining with prescription medications affecting the same physiological pathway as 5-Amino-1MQ (weight loss pathway).

Certificate of Analysis

Every batch of 5-Amino-1MQ sold on Peptide.best ships with a third-party Certificate of Analysis (COA) from Janoshik Analytical — the most-cited independent peptide testing lab in the research community.

Current batch testing summary

• Batch ID: 5AM-2604-E
• Test date: 04/14/2026
• Peptide content (HPLC): 99.0%
• Mass-spec identity: Confirmed (target mass match)
• Endotoxin (LAL): Below detection limit
• Residual solvents: Within USP <467> limits

Download full COA PDF

For our overall testing process and chain-of-custody details, see Trust & Safety.

Q: Is 5-Amino-1MQ legal to purchase?

A: 5-Amino-1MQ is sold on Peptide.best for research purposes where applicable. Legal status varies by jurisdiction. See our disclaimer for full details.

Q: How long until I see effects?

A: Timing depends on protocol, dose, and individual response. Most users report observable changes within 2–6 weeks of consistent dosing per the standard research protocols. See the Dosing & Protocol tab.

Q: Can I stack 5-Amino-1MQ with other peptides?

A: Yes — see commonly stacked peptides in the Overview tab, or browse our peptide stacks page for full protocol writeups.

Q: Why is the price lower than pharmacy retail or other research sites?

A: Peptide.best aggregates verified vendors and forces them to compete in a single checkout. Vendors save on customer-acquisition cost; the savings pass to you. Every batch is still 3rd-party COA tested.

About Aeon Labs

Aeon Labs is one of the six verified vendor partners on Peptide.best. They maintain a 4.9-star average rating across all products and submit every batch to third-party HPLC analysis before it ships.

All Aeon Labs products on Peptide.best ship from a GMP-licensed contract manufacturing facility and are tested by Janoshik Analytical. Cold-chain shipping is included on temperature-sensitive products.